I laid copies of the three books I'd already published on his desk, and I said, "I'm a writer. Please don't do anything to harm my brain." He said, "If you had a kidney disease, you wouldn't hesitate to take medication for it--why are you hesitating with this?" But, see, that only shows how ignorant he was about my family; a Gilbert might very well not medicate a kidney disease, seeing that we're a family who regard any sickness as a sign of personal, ethical, moral failure .

He put me on a few different drugs--Xanax, Zoloft, Wellbutrin, Busperin--until we found the combination that didn't make me nauseated or turn my libido into a dim and distant memory. Quickly, in less than a week, I could feel an extra inch of daylight opening in my mind. Also, I could finally sleep. And this was the real gift, because when you cannot sleep, you cannot get yourself out of the ditch--there's not a chance. The pills gave me those recuperative night hours back, and also stopped my hands from shaking and released the vise grip around my chest and the panic alert button from inside my heart. Still, I never relaxed into taking those drugs, though they helped immediately. It never mattered who told me these medications were a good idea and perfectly safe; I always felt conflicted about it .

Those drugs were part of my bridge to the other side, there's no question about it, but I wanted to be off them as soon as possible. I'd started taking the medication in January of 2003. By May, I was already diminishing my dosage significantly. Those had been the toughest months, anyhow--the last months of the divorce, the last ragged months with David. Could I have endured that time without the drugs, if I'd just held out a little longer? Could I have survived myself, by myself? I don't know. That's the thing about a human life--there's no control group, no way to ever know how any of us would have turned out if any variables had been changed.

I do know these drugs made my misery feel less catastrophic. But

I'm still deeply ambivalent about mood-altering medications. I'm awed by their power, but concerned by their prevalence. I think they need to be prescribed and used with much more restraint in this country, and never without the parallel treatment of psychological counseling. Medicating the symptom of any illness without exploring its root cause is just a classically hare-brained Western way to think that anyone could ever get truly better. Those pills might have saved my life, but they did so only in conjunction with about twenty other efforts I was making simultaneously during that same period to rescue myself, and I hope to never have to take such drugs again .

Though one doctor did suggest that I might have to go on and off antidepressants many times in my life because of my "tendency toward melancholy." I hope to God he's wrong. I intend to do everything I can to prove him wrong, or at least to fight that melancholic tendency with every tool in the shed. Whether this makes me self-defeatingly stubborn, or self-preservingly stubborn,